The Role of Medications in Migraine Treatment

Migraine is a neurological disorder characterized by recurring headaches that can be extremely debilitating. It affects millions of people around the world, causing significant pain, nausea, and sensitivity to light and sound. While there is no cure for migraines, there are a number of migraine pain treatment available to help manage the symptoms and reduce the frequency and intensity of attacks. One of the most common and effective methods of treatment is the use of medications. In this article, we will explore the different types of medications used in migraine treatment and their role in providing relief to sufferers.

Abortive Medications

Abortive medications, also known as acute or rescue medications, are used to provide immediate relief during a migraine attack. These medications work by targeting the underlying causes of migraines, such as inflammation and blood vessel constriction. There are several types of abortive medications available, including: 

– Nonsteroidal anti-inflammatory drugs (NSAIDs): These over-the-counter medications, such as ibuprofen or naproxen sodium, can help reduce pain and inflammation associated with migraines.

– Triptans: These prescription medications, such as sumatriptan or rizatriptan, work by narrowing blood vessels and blocking pain pathways in the brain. They are specifically designed to treat migraines and are effective for many people.

– Ergotamine derivatives: These medications, such as ergotamine or dihydroergotamine, are older treatments for migraines. They work by constricting blood vessels and reducing inflammation.

– Anti-nausea medications: Migraines often cause nausea and vomiting, so medications such as metoclopramide or prochlorperazine can help relieve these symptoms.

– Glucocorticoids: In some cases, corticosteroids like prednisone may be prescribed to reduce inflammation and provide relief during severe or prolonged migraine attacks.

– Opioids: These medications, such as codeine or oxycodone, are sometimes used for severe migraines that do not respond to other treatments. However, they are generally considered a last resort due to the potential for dependence and side effects.

It is important to note that abortive medications should be used as directed by a healthcare professional and should not be overused, as this can lead to medication overuse headaches or rebound headaches. It is also important to discuss with a healthcare provider to determine the most appropriate abortive medication for individual needs and to develop a comprehensive migraine management plan.

Preventive Medications

Preventive medications, also known as prophylactic medications, are used to reduce the frequency and severity of migraine attacks. These medications are typically prescribed to individuals who experience frequent or severe migraines that significantly impact their quality of life. Preventive medications are taken daily, even when the person is not experiencing a migraine attack. 

Rescue Medications

Rescue medications, also known as transitional medications, are used to provide relief during a migraine attack when the prescribed abortive medications are not effective or unavailable. These medications are typically used as a last resort and should not be used frequently to avoid medication overuse headaches. Some commonly used rescue medications include: 

1. Nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen or naproxen sodium. These can help reduce inflammation and relieve pain.

2. Triptans, which are a type of medication specifically designed to treat migraines. They work by constricting blood vessels and reducing inflammation in the brain.

3. Anti-nausea medications, such as metoclopramide or ondansetron, which can help alleviate nausea and vomiting associated with migraines.

4. Ergotamine derivatives, which are older medications that can help relieve migraines by constricting blood vessels and reducing inflammation.

5. Glucocorticoids, such as prednisone, which can be used in severe cases to reduce inflammation and provide relief.

It’s important to note that rescue medications should only be used as directed by a healthcare provider and should not be relied upon as a long-term solution for managing migraines. They are intended to provide temporary relief during an acute attack and should be used sparingly to avoid rebound headaches. If rescue medications are needed frequently, it may be a sign that a different treatment plan or preventative medications should be considered.


Medications play a crucial role in the treatment of migraines by providing relief during an attack and preventing future episodes. It is important to consult with a healthcare professional to determine the most appropriate medication and dosage for individual needs. While medications can be effective in managing migraines, it is also important to explore lifestyle changes and other non-pharmacological approaches, such as stress reduction techniques and dietary modifications, as part of a comprehensive treatment plan.

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Abdus Subhan

Abdus Subhan also writes for Nybreaking,, Techbullion, Filmdaily, waterwaysmagazine, Designerwomen, Businesstomark, ventsmagazine, Stylevanity, and other good quality sites. Contact: