Carbimazole is an anti thyroid agent which reduces the function of thyroid hormones. The medicinal product’s mechanism of action is mainly the reduction of formation of iodotyrosine by inhibition on the iodination of thyroglobulin as well as the reduction of the synthesis of triiodothyronine and thyroxine by inhibition of the coupling reaction between iodotyrosine. It is among the treatments used for hyperactive thyroid function or hyperthyroidism.
As much as people may be concerned, can Carbimazole make you gain weight? As you are being treated for hyperthyroid disease, you may start to gain weight. This is particularly because your body produces fewer thyroid hormones and your metabolism slows down. Basically, treatment of hyperthyroidism will slow down metabolism as the hormone production is either slowed or stopped entirely. As most drug therapy of hyperthyroidism is mainly to reduce the thyroid function, however, both radioactive iodine and surgery destroy all thyroid function. Thus, it will create the hypothyroid condition and need to take a hormone replacement for the rest of life.
Weight gain after hyperthyroidism treatment is a common complaint and some experts in Los Angeles were compelled to study the issue, exactly how much weight people typically gain while being treated for hyperthyroid condition. It is found that many people are gaining weight, with some developing obesity. The data gathered from this study results in high numbers to this side effect of hyperthyroid treatment. Simple awareness of how commonly gaining excess weight may be a big relief. After knowing that weight gain can occur means you can take steps ahead to anticipate the problem and lessen the result.
Following hyperthyroidism treatment, most patients will observe a steady weight gain although they did not practice any changes in their eating habits or exercise. At first, the weight will reach their normal level but then many patients continue to experience further weight gain, approaching overweight or even obesity.
According to the Thyroid Clinic Database at the University Hospitals Birmingham National Health Service Foundation Trust (UHB), data on all adult patients with hyperthyroidism is gathered, whether they were treated with antithyroid drugs, radioiodine (131-I), or both. The data information was collected for patients treated between the year of 2000 and 2014 with three years of followup. In addition, none of the patients had a thyroidectomy or surgical removal of the thyroid; which is another option of overactive thyroid treatment.
Overall, there were 1,373 patients who were evaluated, ages between 18 to 90 years, and their weight was traced over time. During treatment, generally, the men gained about 17.6 pounds while the women gained about 12 pounds. The researchers compared the patients’ weight gain with a control or comparison group. The control of this study involved nearly 11,000 people who did not have an overactive thyroid.
The expected result showed that at the start of drug treatment, those who were diagnosed with overactive thyroid weighed less, on average than the comparison population. However, after treatment, the patients were more likely to reach a level of obesity than the comparison group. Men were 1.7 times more likely meanwhile women, 1.3 times more likely, to gain weight or to be considered obese.
Nevertheless, it is possible to lose weight during the treatment. Normally, your weight loss may be slow while your body adjusts and compensates for your new lower metabolism. If you follow a healthy diet, however, it will help you reach a healthy body weight.
Your metabolism controls the rate you burn calories which suggests that the higher your metabolism is, the easier it is for you to lose weight. There are three parts to your metabolism as to be listed; your Basal Metabolic Rate (BMR), physical activity and digestion. Besides, the number of calories burned may be increased during digestion by making changes in your diet, plus, you can boost the energy needed for physical activity by exercising more. Exercises that build muscle mass such as strength training exercises will increase your BMR because muscle uses more energy at rest.
