What is the IHC test?
Immunohistochemistry is staining cells and tissues with antibodies to visualize specific proteins. An IHC or immunohistochemistry test is a blood test that measures the levels of three hormones. These hormones are prolactin, luteinizing hormone (LH), and follicle-stimulating hormone (FSH). Prolactin is responsible for milk production in women who are breastfeeding. LH and FSH are responsible for ovulation and fertility in women. IHC test is a diagnostic procedure in which doctors use a microscope to examine tissues for antibodies.
In this test, doctors look for specific proteins associated with certain diseases, such as cancer. The test can help doctors diagnose diseases, plan treatment, and predict a person’s prognosis. In IHC, doctors use antibodies that bind specific proteins.
What is the normal range for IHC?
IHC test measures the amount of HER2 protein on the cells’ surface of a breast cancer tissue sample. HER2, or human epidermal growth factor receptor 2, is a protein that enables cancer cells to proliferate. IHC test assigns a score ranging from 0 to 3+ for HER2 receptor protein. A score of 3 or higher is considered HER2 positive. It is referred to as HER2 negative if the score is 0 to 1+. When the score is 2 or higher, it is considered borderline. The results will vary depending on the antibodies and techniques used. A positive result for IHC will show up as a brown or black color on the tissue sample. A negative result will be either no or faint color change. Different laboratories use varying methods for analyzing the results of the IHC test. Discuss your test result with your doctor for a better understanding.
What is the IHC test price?
IHC test price ranges from Rs. 6500 to 8500. The cost depends on the type of test being performed and the location where it is performed. In Mumbai, the IHC test costs ₹ 8500, whereas, in Delhi, it is ₹ 6500.
What is the result of an IHC test?
The result of an IHC test is reported as positive or negative.
A negative result means that the antibodies did not bind to the protein. This may be a sign that you do not have the disease. It also indicates that you are not a carrier of a particular genetic mutation. A negative test determines that you have a low risk of developing the specific disease being tested.
A positive result means that the antibodies used in the test are bound to the protein tested. This may be a sign of disease. However, further genetic testing is advised because you may have an inherited genetic disorder.
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