The icsi procedure is another step of IVF techniques, intracytoplasmic sperm injection is the process by which a sperm is injected into an egg and then the fertilized egg is placed in the uterus. Sperm or if IVF has previously resulted in eggs not being fertilized.
What is the icsi procedure?
Intracytoplasmic sperm injection can be a treatment used to treat patients with severe male infertility for whom conventional IVF has been unsuitable or has failed or resulted in very poor fertilization in the past.
Its main advantage over routine in vitro fertilization is that we only need one sperm to inject each egg, thus fertilization can be achieved in cases where the sperm count is severely low, sperm motility is poor, or the numbers of normally shaped sperm are low.
It may also be used in cases where sperm must be surgically removed from the testicle, or when high numbers of anti-sperm antibodies are present.
Who is a candidate for intracytoplasmic sperm injection?
If a woman has trouble conceiving naturally, and her husband has low sperm counts, she would be a suitable candidate for intracytoplasmic sperm injection (ICSI). To determine if this fertility treatment is right for you, talk to your doctor about your options.
How is the icsi procedure done?
Intracytoplasmic sperm injection was first introduced in 1992. It involves injecting a single sperm directly into the center of each egg. The fertilized egg can then be transferred into the woman’s uterus, as in a very normal IVF cycle. ICSI is just another step towards routine IVF, which is performed in-vitro.
Are all eggs injected and does the injection cause any harm?
After the eggs are collected, the eggs are prepared and evaluated by an embryologist. Only mature eggs will be suitable for injection, and not all eggs collected will reach the desired maturity. Usually, we will be able to inject at least 80% of the eggs collected.
The icsi procedure destroys a small number of oocytes (less than 10%). The damage usually becomes apparent during or after the procedure. No eggs damaged during this method of treatment will be used.
What are the steps of the icsi procedure?
At Bedaya Hospital, intracytoplasmic sperm injection (ICSI) is considered as part of the in vitro fertilization (IVF) procedure. It is a process in which one sperm is injected into the cytoplasm (center) of each egg by an embryologist. After the egg is injected with sperm, the embryologist will monitor the egg for the next day or so. If fertilization and maturation of the fetus occur correctly, it will be transferred to the uterine cavity.
Fertility drugs are used to produce multiple eggs in the ovaries during an IVF cycle. Once the follicles (egg sacs) have matured, your doctor will remove eggs from your ovaries. Most patients receive light intravenous sedation during this procedure.
During the egg retrieval, the husband will be asked for a semen sample. The sperm is evaluated and the best sperm is selected for ICSI.
After the eggs and sperm are collected, ICSI takes place in an embryology laboratory. Your nurse will call the next day to let you know the fertilization results.
Frequently asked questions about the icsi procedure
How can the icsi procedure help boost the chance of conception?
One sperm is selected for the egg injection. If the procedure is successful, the embryos will be transferred after 5-6 days. ICSI can be a good option for patients for whom egg fertilization is low or unlikely.
Is there anything we would like to try to arrange before this procedure?
You must take fertility drugs during your treatment cycle so that your ovaries produce multiple eggs. Also, abstain from sex two or three days before egg retrieval to increase the quality of the semen. Ask your nurse or andrologist to determine if there are other recommendations for you.
When will we all know if this treatment works?
In general, you will receive a phone call the next day from your nurse with your fertility results. A pregnancy biopsy is done about two weeks after the embryo transfer.
When should an icsi procedure be selected?
You can choose an ICSI procedure if the husband has low quality sperm or if you have a history of IVF failure.