Guidelines for COVID-19 Antibody Key Testing

Nowadays, new antibody test kits are coming that will change the landscape of Covid-19 testing. However, there are two ways for testing Coronavirus – One that measures the actual virus and the other measures the body reaction to the virus.

The first test which is usually named “Genome test” helps in detecting the presence of viral genes by using swabbed samples. The sample usually has been taken from the nose and throat. Its result can be seen either in one day or it takes a week. On the other hand, the second test named as “Serology Test” detects the presence of SARS- CoV-2 in the blood. Their results are obtained by using a finger-prick blood test. Like the Genome test, the COVID-19 antibody test kit is rapidly diagnostic and gives the people an outcome within a couple of times.

The Antibody test enumerates the number of (IgM) immunoglobulin M and (IgG) immunoglobulin G antibodies in the blood. The presence of IgM appears first and invades the organisms. It shows the exposure to the virus. Due to this result, the virus could be easily identified. Its feature does not have any small importance and plays a major role in transmission. 

COVID-19 antibody test kit guidelines

1: The Serologic test for Covid-19 now has Emergency use Authorization by Food and Drug Administration. They also have reviewed the performances independently.

2: At present, there is no recognized advantage of tests whether for IgG, IgM, etc.

3: It is highly recommendable to reduce the false-positive tests and start analyzing the high specificity by testing the populations. These can be done with the rising exposure to SARS Cov-2.

4: The orthogonal testing algorithm means employing two individual tests in sequence & can be used when the positive analytic value of a single test is low. 

5: The Antibodies are more commonly detected within 1-3 weeks after symptoms become onset. Also at that time, the infection can be greatly decreased. Moreover, the additional data are also needed for public health recommendations and that is completely based on the serologic test. It also includes the decision on physical distancing and using well-protective equipment. 

6: The serology test provides both positive as well as negative results for the presence and absence of antibodies. These antibodies show the most common detectable symptom of 1-3 weeks. It might be possible at that point the infectiousness gets decreased. But it can also be possible that the immunity from infection may get developed in the future. Therefore, the evidence for it is not conclusive yet. 

7: While using the test with high sensitivity increases the probability of getting true positive results. Conversely, testing people where Covid-19 cases are low increases the chances of false positives because the person who has been infected hasn’t shown the Covid-19 symptoms.